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Nathan Goodyear

NRF2 activation restores disease related metabolic ... [PLoS One. 2011] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...21747966

NRF2 Parkinson's disease neurodegenerative disorders

shared by Nathan Goodyear on 14 Dec 11 - No Cached
  • Nathan Goodyear on 14 Dec 11
     
    NRF2 could be a new target of therapy for people with Parkinson's and other neurodegenerative disorders.
Nathan Goodyear

Mary Ann Liebert, Inc. - Journal of Neurotrauma - 0(ja): - 0 views

www.liebertonline.com/...neu.2011.1922

sulphoraphane Nrf2 glutathione inflammation neuroinflammation oxidative damage cytokines

shared by Nathan Goodyear on 24 Aug 11 - No Cached
  • Nathan Goodyear on 24 Aug 11
     
    sulphoraphane activates Nrf2 pathway, which promotes Glutathione production, plays role in reducing oxidative damage and neuroinflammation
Nathan Goodyear

Unveiling the Mechanisms for Decreased Glutathione in Individuals with HIV Infection - 0 views

connection.ebscohost.com/...ione-individuals-hiv-infection

glutathione GSH Nrf2 GSSG HIV inflammation oxidative Stress

shared by Nathan Goodyear on 07 Jan 15 - No Cached
  • Nathan Goodyear on 07 Jan 15
     
    men with HIV have GSH depleted macrophages.  GSH is the reduced, ready to act form of Glutathione.  In contrast, the macrophages were high in the oxidized form of Glutathione--GSSG.  In HIV, the high inflammation increased oxidative stress, likely overwhelmed Nrf2 activation and resulted in decreased GSH synthase transcription and thus decreased Glutathione production balance.
Nathan Goodyear

An update of Nrf2 activators and inhibitors in cancer prevention/promotion | Cell Commu... - 0 views

biosignaling.biomedcentral.com/...s12964-022-00906-3

cancer Nrf2

shared by Nathan Goodyear on 04 Nov 22 - No Cached
  • Nathan Goodyear on 04 Nov 22
     
    Protects cells against endogenous/exogenous stressors. Intermittent protects cells; chronic activation used by cancer to promote survival.
Nathan Goodyear

Nrf2 activation by sulforaphane restores the age-related decrease of TH1 immunity: Role... - 0 views

www.jacionline.org/...abstract

sulforaphane nrf2 Th1 Th2

shared by Nathan Goodyear on 22 Mar 11 - No Cached
  • Nathan Goodyear on 22 Mar 11
     
    sulforaphane upregulates Th1 immunity; which aging shifts to Th2 dominance
Nathan Goodyear

Enhancement of dopaminergic activity and region-specific activation of Nrf2-ARE pathway... - 0 views

www.ncbi.nlm.nih.gov/...26893122

low T Testosterone low Testosterone dopamine hormones male hormones

shared by Nathan Goodyear on 22 Feb 16 - No Cached
  • Nathan Goodyear on 22 Feb 16
     
    Testosterone stimulates dopaminergic activity in rat study.  
Nathan Goodyear

Oxidative stress in health and disease: The therapeutic potential of Nrf2 activation - 0 views

www.sciencedirect.com/...S0098299711000501

oxidative Stress health disease

shared by Nathan Goodyear on 05 Dec 14 - No Cached
  • Nathan Goodyear on 05 Dec 14
     
    Oxidative Stress
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